Title : Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans.

Pub. Date : 2022 Mar 29

PMID : 35354052






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Env is heavily glycosylated with host-derived N-glycans, and many bnAbs bind to, or are dependent upon, Env glycans for neutralization. n-glycans endogenous retrovirus group K member 20 Homo sapiens
2 Although glycan-binding bnAbs are frequently detected in HIV-infected individuals, attempts to elicit them have been unsuccessful because of the poor immunogenicity of Env N-glycans. n-glycans endogenous retrovirus group K member 20 Homo sapiens