Title : Local nebulization of 1α,25(OH)2D3 attenuates LPS-induced acute lung inflammation.

Pub. Date : 2022 Mar 29

PMID : 35351141






1 Functional Relationships(s)
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1 RESULTS: Local 1alpha,25(OH)2D3 reduced LPS-induced inflammatory cells in bronchoalveolar lavage (BAL) in VDS (absolute number of cells: - 57% and neutrophils - 51% p < 0.01) and tended to diminish LPS-increased CXCL5 BAL levels in VDS (- 40%, p = 0.05) while it had no effect on CXCL1 and CXCL2 in BAL and mRNA in lung of VDS and VDD. methyl 5-methyl-3-(1,2-oxazol-5-yl)-1H-pyrazole-4-carboxylate chemokine (C-X-C motif) ligand 2 Mus musculus