Title : IL-17A mediates pyroptosis via the ERK pathway and contributes to steroid resistance in CRSwNP.

Pub. Date : 2022 Mar 26

PMID : 35346673






4 Functional Relationships(s)
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1 IL-17A Mediates Pyroptosis via ERK Pathway and Contributes to Steroid Resistance in CRSwNP. Steroids interleukin 17A Homo sapiens
2 Moreover, IL-17A-induced pyroptosis contributes to steroid resistance by affecting glucocorticoid receptor (GR)alpha and GRbeta expression, and the inhibition of pyroptotic proteins partially abolished IL-17A-induced steroid resistance in hNECs. Steroids interleukin 17A Homo sapiens
3 Moreover, IL-17A-induced pyroptosis contributes to steroid resistance by affecting glucocorticoid receptor (GR)alpha and GRbeta expression, and the inhibition of pyroptotic proteins partially abolished IL-17A-induced steroid resistance in hNECs. Steroids interleukin 17A Homo sapiens
4 Moreover, IL-17A-induced pyroptosis contributes to steroid resistance by affecting glucocorticoid receptor (GR)alpha and GRbeta expression, and the inhibition of pyroptotic proteins partially abolished IL-17A-induced steroid resistance in hNECs. Steroids interleukin 17A Homo sapiens