Title : Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages: implications for dtymk mutation-caused neurodegenerative disorders.

Pub. Date : 2022 Mar 27

PMID : 35346037






1 Functional Relationships(s)
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1 Here we used the zebrafish model and studied (i) TMPK, an enzyme required for both the de novo and the salvage pathways of dTTP synthesis, and (ii) thymidine kinases (TK) of the salvage pathway in order to understand their role in neuropathology. thymidine 5'-triphosphate deoxythymidylate kinase Homo sapiens