Title : A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.

Pub. Date : 2022 May

PMID : 35344983






1 Functional Relationships(s)
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1 Attractive pharmacological targets to impede viral entry include type-II transmembrane serine proteases (TTSPs), such as TMPRSS2, whose essential role in the virus lifecycle is to cleave the viral spike protein to expose the fusion peptide for cell entry5,6. Serine surface glycoprotein Severe acute respiratory syndrome coronavirus 2