Pub. Date : 2022 Mar 4
PMID : 35336938
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The spike proteins of enveloped viruses are transmembrane glycoproteins that typically undergo post-translational attachment of palmitate on cysteine residues on the cytoplasmic facing tail of the protein. | Cysteine | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
2 | Here, we report that palmitoylation of the first five cysteine residues of the C-terminal cysteine-rich domain of the SARS-CoV-2 S protein are indispensable for infection, and palmitoylation-deficient spike mutants are defective in membrane fusion. | Cysteine | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
3 | Here, we report that palmitoylation of the first five cysteine residues of the C-terminal cysteine-rich domain of the SARS-CoV-2 S protein are indispensable for infection, and palmitoylation-deficient spike mutants are defective in membrane fusion. | Cysteine | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |