Title : Inhibition of Ceramide Glycosylation Enhances Cisplatin Sensitivity in Cholangiocarcinoma by Limiting the Activation of the ERK Signaling Pathway.

Pub. Date : 2022 Feb 28

PMID : 35330102






2 Functional Relationships(s)
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1 The expression of GCS and GBA2 was induced in CCA cell lines following low-dose cisplatin treatment. Cisplatin UDP-glucose ceramide glucosyltransferase Homo sapiens
2 Taken together, inhibition of the GCS increased cisplatin-induced CCA apoptosis via the inhibition of the ERK signaling pathway. Cisplatin UDP-glucose ceramide glucosyltransferase Homo sapiens