Title : Is There a Role for Epigenetic Therapies in Modulating DNA Damage Repair Pathways to Enhance Chemotherapy and Overcome Drug Resistance?

Pub. Date : 2022 Mar 16

PMID : 35326684






1 Functional Relationships(s)
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1 For genes such as MGMT and BRCA1, promoter DNA methylation is associated with chemosensitivity to alkylating agents and platinum coordination complexes, respectively, and they have use as biomarkers directing patient treatment options. Platinum BRCA1 DNA repair associated Homo sapiens