Title : Bisphenol A exposure triggers the malignant transformation of prostatic hyperplasia in beagle dogs via cfa-miR-204/KRAS axis.

Pub. Date : 2022 Apr 15

PMID : 35325610






2 Functional Relationships(s)
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1 Based on microRNA (miRNA) microarray screening and functional enrichment analysis, BPA might facilitate the progression of prostate tumorigenesis in beagle dogs via cfa-miR-204 and its downstream target KRAS oncogene. bisphenol A KRAS proto-oncogene, GTPase Canis lupus familiaris
2 These findings provide a series of underlying targets for preventing the initiation and metastasis of BPA-induced prostatic hyperplasia and tumorigenesis, while the regulatory relationship headed with KRAS requires further investigation. bisphenol A KRAS proto-oncogene, GTPase Canis lupus familiaris