Pub. Date : 2022 Apr 21
PMID : 35325017
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Daphnetin inhibits alpha-MSH-induced melanogenesis via PKA and ERK signaling pathways in B16F10 melanoma cells. | daphnetin | mitogen-activated protein kinase 1 | Mus musculus |
| 2 | Moreover, daphnetin downregulated the phosphorylation of PKA, ERK, MSK1, and CREB. | daphnetin | mitogen-activated protein kinase 1 | Mus musculus |
| 3 | Our data propose that daphnetin inhibits melanogenesis via modulating both the PKA/CREB and the ERK/MSK1/CREB pathways. | daphnetin | mitogen-activated protein kinase 1 | Mus musculus |