Title : Sodium butyrate alleviates LPS-induced kidney injury via inhibiting TLR2/4 to regulate rBD2 expression.

Pub. Date : 2022 Mar 23

PMID : 35322444






3 Functional Relationships(s)
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1 Rat beta-defensin 2 (rBD2), as estimated by mRNA level, was significantly higher in LPS-treated kidneys, whereas the changes of rBD2 reduced in NaB-treated kidneys. nab defensin beta 4 Rattus norvegicus
2 Rat beta-defensin 2 (rBD2), as estimated by mRNA level, was significantly higher in LPS-treated kidneys, whereas the changes of rBD2 reduced in NaB-treated kidneys. nab defensin beta 4 Rattus norvegicus
3 Mechanistically, the present study indicates that NaB has nephroprotective activity resulting from modulation of TLR2/4 to regulate rBD2 expression hence curbing inflammation. nab defensin beta 4 Rattus norvegicus