Title : Preferential inhibitory effect of nifedipine on angiotensin II-induced renal vasoconstriction.

Pub. Date : 1986 Oct

PMID : 3531005






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1 Furthermore, a greater renal vasodilation induced by intrarenal bolus injections of nifedipine (1,3, and 10 micrograms) but not by acetylcholine (0.1 and 0.3 microgram) was observed during the reduction in the perfusion pressure of the contralateral kidney to approximately 50 mm Hg, which resulted in an increase in plasma renin activity and plasma angiotensin II concentration but no change in plasma norepinephrine concentration. Nifedipine renin Canis lupus familiaris
2 There was a significant positive correlation between plasma renin activity and plasma angiotensin II concentration before nifedipine injections and the subsequent increase in renal blood flow produced by each dose of nifedipine. Nifedipine renin Canis lupus familiaris
3 There was a significant positive correlation between plasma renin activity and plasma angiotensin II concentration before nifedipine injections and the subsequent increase in renal blood flow produced by each dose of nifedipine. Nifedipine renin Canis lupus familiaris