Title : Role of Paralogue of XRCC4 and XLF in DNA Damage Repair and Cancer Development.

Pub. Date : 2022

PMID : 35309348






1 Functional Relationships(s)
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1 One of the newly identified proteins is Paralogue of XRCC4 and XLF (PAXX), which acts as a scaffold that is required to stabilize the KU70/80 heterodimer at DSBs sites and promotes the assembly and/or stability of the cNHEJ machinery. dsbs X-ray repair cross complementing 4 Homo sapiens