Pub. Date : 2022
PMID : 35299960
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | miR-218-5p Induces Interleukin-1beta and Endovascular Trophoblast Differentiation by Targeting the Transforming Growth Factor beta-SMAD2 Pathway. | mir-218-5p | SMAD family member 2 | Homo sapiens |
| 2 | On the other hand, overexpression of SMAD2 reduced IL1beta levels and blocked the stimulatory effects of miR-218-5p on IL1B expression, trophoblast migration and endothelial-like network formation. | mir-218-5p | SMAD family member 2 | Homo sapiens |
| 3 | These results suggest that miR-218-5p inhibits the TGFbeta/SMAD2 pathway to induce IL1beta and enEVT differentiation. | mir-218-5p | SMAD family member 2 | Homo sapiens |