Title : Downregulation of secreted frizzled-related protein 4 inhibits hypoxia/reoxygenation injury in diabetic cardiomyocytes by protein tyrosine phosphatase nonreceptor type 12.

Pub. Date : 2022 Mar

PMID : 35290144






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SFRP4 expression was upregulated in a high-glucose-stimulated H/R cardiomyocyte model. Glucose secreted frizzled related protein 4 Homo sapiens
2 The interference of SFRP4 promoted cell viability, inhibited the inflammatory and oxidative stress response of H/R cardiomyocytes induced by high glucose. Glucose secreted frizzled related protein 4 Homo sapiens
3 PTPN12 overexpression reversed the inhibitory effect of sh-SFRP4 on H/R cardiomyocyte damage induced by high glucose. Glucose secreted frizzled related protein 4 Homo sapiens