Title : Cardiorenal protective effects of sodium-glucose cotransporter 2 inhibition in combination with angiotensin II type 1 receptor blockade in salt-sensitive Dahl rats.

Pub. Date : 2022 May 1

PMID : 35285452






1 Functional Relationships(s)
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1 The protein expression levels of Na+/H+ exchanger isoform 3 (NHE3) and Na+-K+-Cl- cotransporter 2 (NKCC2) in the kidney were significantly decreased with losartan monotherapy and combination treatment, but not with ipragliflozin monotherapy. ipragliflozin solute carrier family 12 member 1 Rattus norvegicus