Pub. Date : 2022 Apr 15
PMID : 35283112
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Captopril alleviates glucocorticoid-induced osteonecrosis of the femoral head by mediating the ACE2/ Ang-(1-7)/Mas receptor cascade. | Captopril | angiogenin | Rattus norvegicus |
2 | Taken together, these findings demonstrate for the first time that CAP exerts anti-inflammatory, antioxidant, anti-apoptotic, and osteoprotective effects against GIONFH by activating the ACE2/Ang-(1-7)/Mas receptor signaling pathway, which expands a new strategy for the treatment of orthopedic diseases. | Captopril | angiogenin | Rattus norvegicus |