Title : TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.

Pub. Date : 2022 May 10

PMID : 35257795






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 INT-777, a 6alpha-ethyl-23(S)-methyl derivative of cholic acid (S-EMCA), acts as an agonist for Takeda G protein-coupled receptor-5 (TGR5) and has neuroprotective properties. Cholic Acid G protein-coupled bile acid receptor 1 Mus musculus