Title : Blocking SARS-CoV-2 Delta Variant (B.1.617.2) Spike Protein Receptor-Binding Domain Binding with the ACE2 Receptor of the Host Cell and Inhibiting Virus Infections Using Human Host Defense Peptide-Conjugated Graphene Quantum Dots.

Pub. Date : 2022 Mar 8

PMID : 35252734






2 Functional Relationships(s)
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1 Blocking SARS-CoV-2 Delta Variant (B.1.617.2) Spike Protein Receptor-Binding Domain Binding with the ACE2 Receptor of the Host Cell and Inhibiting Virus Infections Using Human Host Defense Peptide-Conjugated Graphene Quantum Dots. Graphite surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 Herein, we report for the first time that human host defense neutrophil alpha-defensin HNP1 and human cathelicidin LL-37 peptide-conjugated graphene quantum dots (GQDs) have the capability to prevent the delta variant virus entry into the host cells via blocking SARS-CoV-2 delta variant (B.1.617.2) spike protein receptor-binding domain (RBD) binding with host cells" angiotensin converting enzyme 2 (ACE2). Graphite surface glycoprotein Severe acute respiratory syndrome coronavirus 2