Title : The effect of Bruton's tyrosine kinase inhibitor ibrutinib on atherothrombus formation under stenotic flow conditions.

Pub. Date : 2022 Apr

PMID : 35247800






2 Functional Relationships(s)
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1 The Btk inhibitor ibrutinib has been shown to selectively block platelet adhesion to atherosclerotic plaque material under laminar arterial flow. ibrutinib Bruton tyrosine kinase Homo sapiens
2 CONCLUSION: Treatment of patients with haematological disorders with the Btk inhibitor ibrutinib reduces in vitro platelet deposition, thrombus size and contraction on human atherosclerotic plaque around a stenosis when compared to patients not receiving ibrutinib. ibrutinib Bruton tyrosine kinase Homo sapiens