Pub. Date : 2022 Mar
PMID : 35246010
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Besides, bupivacaine attenuated the phosphorylation of PI3K, Akt, and mTOR. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In addition, bupivacaine suppressed the growth of xenografted tumors, induced apoptosis and ferroptosis, and inhibited the activity of PI3K/AKT signaling pathway in xenografted tumors. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Bupivacaine could induce apoptosis and ferroptosis by inhibiting PI3K/Akt signaling pathway in bladder cancer cells. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |