Pub. Date : 2022 Mar 3
PMID : 35241098
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RESULTS: CoQ10 treatment significantly increased serum adiponectin levels at week 12 (165 (0, 362) ng/mL, p < 0.001) and at week 24 (523 (0, 1056) ng/mL, p < 0.001)), which was significant different compared with placebo (p < 0.001). | coenzyme Q10 | adiponectin, C1Q and collagen domain containing | Homo sapiens |
2 | The increase of adiponectin was negative associated with decrease in index of homeostasis model assessment of insulin resistance (HOMA-IR, r = - 0.465, p = 0.001), triglyceride (TG, r = - 0.297, p = 0.047), and low-density lipoprotein cholesterol (LDL-c, r = - 0.440, p = 0.002) at week 24 only in CoQ10-treated group. | coenzyme Q10 | adiponectin, C1Q and collagen domain containing | Homo sapiens |
3 | The beneficial effect of CoQ10 on glucolipid profile was mediated by adiponectin. | coenzyme Q10 | adiponectin, C1Q and collagen domain containing | Homo sapiens |