Title : Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.

Pub. Date : 2022 Mar 3

PMID : 35241098






3 Functional Relationships(s)
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1 RESULTS: CoQ10 treatment significantly increased serum adiponectin levels at week 12 (165 (0, 362) ng/mL, p < 0.001) and at week 24 (523 (0, 1056) ng/mL, p < 0.001)), which was significant different compared with placebo (p < 0.001). coenzyme Q10 adiponectin, C1Q and collagen domain containing Homo sapiens
2 The increase of adiponectin was negative associated with decrease in index of homeostasis model assessment of insulin resistance (HOMA-IR, r = - 0.465, p = 0.001), triglyceride (TG, r = - 0.297, p = 0.047), and low-density lipoprotein cholesterol (LDL-c, r = - 0.440, p = 0.002) at week 24 only in CoQ10-treated group. coenzyme Q10 adiponectin, C1Q and collagen domain containing Homo sapiens
3 The beneficial effect of CoQ10 on glucolipid profile was mediated by adiponectin. coenzyme Q10 adiponectin, C1Q and collagen domain containing Homo sapiens