Title : Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss.

Pub. Date : 2022 Mar 8

PMID : 35238644






1 Functional Relationships(s)
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1 Herein, based on pharmacological and genetic interventions, we found that a high dose of sirolimus resulted in severe hearing loss by reducing the mTORC2/AKT signaling pathway in the cochlea. Sirolimus thymoma viral proto-oncogene 1 Mus musculus