Title : Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.

Pub. Date : 2022 May 1

PMID : 35231441






1 Functional Relationships(s)
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1 CESC-exomiR-125-5p inhibited TBHP-NPCs apoptosis by inhibiting SUV39H1, bax, MMP13, and p62 expression, while increased bcl2, ACAN, LC3-II/I expression, and the fluorescence intensity of GFP-LC3, thereby alleviating rat IDD. tert-Butylhydroperoxide KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus