Title : Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation.

Pub. Date : 2022 Feb 15

PMID : 35215995






1 Functional Relationships(s)
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1 The ROS scavenger N-acetyl-l-cysteine (NAC) and the p53 specific inhibitor Pifithrin-alpha (PFT-alpha) suppressed PEDV-induced apoptosis and impeded viral replication, suggesting that ROS and p53 play an important role in PEDV-induced apoptosis and viral replication. Acetylcysteine tumor protein p53 Homo sapiens