Title : Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication.

Pub. Date : 2022 Jan 18

PMID : 35215765






2 Functional Relationships(s)
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1 A nanoluciferase reporter clone with deletion of spike (S), envelope (E), and membrane (M) proteins exhibited high levels of transient replication, was inhibited by remdesivir, and therefore could function as an efficient non-infectious subgenomic replicon system. remdesivir surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 A nanoluciferase reporter clone with deletion of spike (S), envelope (E), and membrane (M) proteins exhibited high levels of transient replication, was inhibited by remdesivir, and therefore could function as an efficient non-infectious subgenomic replicon system. remdesivir surface glycoprotein Severe acute respiratory syndrome coronavirus 2