Title : Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate.

Pub. Date : 2022 Feb 21

PMID : 35215371






1 Functional Relationships(s)
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1 In the current study, a small library of sulfated glycans and highly negatively charged compounds, including pentosan polysulfate (PPS), mucopolysaccharide polysulfate (MPS), sulfated lactobionic acid, sulodexide, and defibrotide, was assembled and evaluated for binding to the S-proteins and inhibition of viral infectivity in vitro. Polysaccharides surface glycoprotein Severe acute respiratory syndrome coronavirus 2