Title : Effect of GSTA1 Variants on Busulfan-Based Conditioning Regimen Prior to Allogenic Hematopoietic Stem-Cell Transplantation in Pediatric Asians.

Pub. Date : 2022 Feb 11

PMID : 35214132






3 Functional Relationships(s)
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1 However, the response of busulfan is highly variable and unpredictable, whereby the pharmacogenetic interference of glutathione S-transferase (GST) has strong evidence in Caucasians and some adult Asians but not in pediatric Asian patients. Busulfan glutathione S-transferase kappa 1 Homo sapiens
2 However, the response of busulfan is highly variable and unpredictable, whereby the pharmacogenetic interference of glutathione S-transferase (GST) has strong evidence in Caucasians and some adult Asians but not in pediatric Asian patients. Busulfan glutathione S-transferase kappa 1 Homo sapiens
3 This study was aimed at investigating the associations of GST genetic polymorphisms with variations in the pharmacokinetic (PK) properties of busulfan in pediatric Asian patients. Busulfan glutathione S-transferase kappa 1 Homo sapiens