Pub. Date : 2022 Feb 18
PMID : 35204825
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Redox sensitivity of p53 functions is supported by (i) thioredoxin-dependent reduction of p53 disulfides, (ii) inhibition of the thioredoxin-dependent deoxyribonucleotide synthesis by p53 binding to RRM2B and (iii) changed intracellular distribution of p53 through its oxidation by CHCHD4 in the mitochondrial intermembrane space. | Disulfides | thioredoxin | Homo sapiens |