Pub. Date : 2022 Feb 18
PMID : 35203369
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Selective PPARalpha Modulator Pemafibrate and Sodium-Glucose Cotransporter 2 Inhibitor Tofogliflozin Combination Treatment Improved Histopathology in Experimental Mice Model of Non-Alcoholic Steatohepatitis. | 6-((4-ethylphenyl)methyl)-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)spiro(isobenzofuran-1(3H),2'-(2H)pyran)-3',4',5'-triol | solute carrier family 5 (sodium/glucose cotransporter), member 2 | Mus musculus |
2 | In this study, we evaluated the effect of the selective PPARalpha modulator (SPPARMalpha) pemafibrate (Pema) and sodium-glucose cotransporter 2 (SGLT2) inhibitor tofogliflozin (Tofo) combination treatment on pathological progression in the liver of a mouse model of NASH (STAM) at two time points (onset of NASH progression and HCC survival). | 6-((4-ethylphenyl)methyl)-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)spiro(isobenzofuran-1(3H),2'-(2H)pyran)-3',4',5'-triol | solute carrier family 5 (sodium/glucose cotransporter), member 2 | Mus musculus |