Title : Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration.

Pub. Date : 2022 May

PMID : 35202704






3 Functional Relationships(s)
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1 Retinal iron overload has been reported in several mouse disease models with systemic or neural retina-specific knockout (KO) of homologous ferroxidases ceruloplasmin (Cp) and hephaestin (Heph). Iron hephaestin Mus musculus
2 Retinal iron overload has been reported in several mouse disease models with systemic or neural retina-specific knockout (KO) of homologous ferroxidases ceruloplasmin (Cp) and hephaestin (Heph). Iron hephaestin Mus musculus
3 Cp and Heph can potentiate ferroportin (Fpn) mediated cellular iron export. Iron hephaestin Mus musculus