Title : Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation.

Pub. Date : 2022 Mar 18

PMID : 35194983






1 Functional Relationships(s)
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1 Additionally, 32 genes were identified as under positive selection in cetaceans, including key purine salvage enzymes (i.e., HPRT1), suggesting improved re-utilization of non-recyclable purines avoid hypoxanthine accumulation and reduce oxidative stress. Hypoxanthine hypoxanthine phosphoribosyltransferase 1 Homo sapiens