Title : Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation.

Pub. Date : 2022

PMID : 35186762






1 Functional Relationships(s)
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1 The aim of this study was to investigate the metabolic alterations associated with metformin (MET), an anti-diabetic agent when combined with two antifolate drugs: trimethoprim (TMP) or methotrexate (MTX), and how metabolic changes within the cancer cell may be used to increase cellular death. Metformin SAFB like transcription modulator Homo sapiens