Pub. Date : 2022 May
PMID : 35184257
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BCL2L1 is identified as a target of naringenin in regulating ovarian cancer progression. | naringenin | BCL2 like 1 | Homo sapiens |
| 2 | BCL2L1 was identified as the candidate target of naringenin against OC. | naringenin | BCL2 like 1 | Homo sapiens |
| 3 | Naringenin decreased BCL2L1 expression and inactivated the PI3K/Akt pathway in OC cells. | naringenin | BCL2 like 1 | Homo sapiens |
| 4 | Naringenin inhibited cell proliferation and increased the apoptotic rate in OC cells, while these effects were partially abolished by BCL2L1 overexpression and treatment with 740Y-P, a PI3K activator. | naringenin | BCL2 like 1 | Homo sapiens |
| 5 | In conclusion, naringenin exerted an anti-tumor effect on OC progression via inactivation of the PI3K/Akt/BCL2L1 pathway. | naringenin | BCL2 like 1 | Homo sapiens |