Pub. Date : 2022 Jun
PMID : 35179299
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation. | naringin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | Likewise, si-Nrf2 blocked the protective effect of naringin against APAP-induced liver injury. | naringin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 3 | Collectively, our results indicate that naringin may be a potent CHAC2 activator, alleviating APAP-induced hepatitis via CHAC2-mediated activation of the Nrf2 pathway. | naringin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |