Title : Differential expression of PD‑L1 and PD‑L2 is associated with the tumor microenvironment of TILs and M2 TAMs and tumor differentiation in non‑small cell lung cancer.

Pub. Date : 2022 Apr

PMID : 35169863






3 Functional Relationships(s)
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1 The TIL and M2 TAM densities were also associated with the expression of PD-L2 on both TCs (P=0.0494 and P=0.0452, respectively) and ICs (P=0.0048 and P=0.0125, respectively). 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide programmed cell death 1 ligand 2 Homo sapiens
2 However, there was no correlation between the percentage of PD-L1-positive TCs and the percentage of PD-L2-positive TCs (r=0.019; P=0.8049). 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide programmed cell death 1 ligand 2 Homo sapiens
3 By contrast, tumor differentiation was inversely associated with the PD-L2 expression on both TCs and ICs (P=0.0260 and P=0.0326, respectively). 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide programmed cell death 1 ligand 2 Homo sapiens