Pub. Date : 1986 Feb
PMID : 3516962
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Escherichia coli isolates which synthesised the extremely common "TEM-1" plasmid mediated beta-lactamase were more resistant to the alpha-aminopenicillins, ampicillin, mezlocillin and azlocillin, than were strains which lacked this enzyme. | Mezlocillin | hypothetical protein | Escherichia coli |
| 2 | However, many TEM-1+ isolates remained sensitive to therapeutic concentrations of mezlocillin (less than 64 mg/l), whereas virtually none was susceptible to such levels of ampicillin or azlocillin. | Mezlocillin | hypothetical protein | Escherichia coli |
| 3 | Transconjugants of E. coli K12 into which we introduced various TEM-1 coding plasmids similarly acquired lower levels of resistance to mezlocillin than to ampicillin and azlocillin. | Mezlocillin | hypothetical protein | Escherichia coli |