Pub. Date : 2022 Feb 14
PMID : 35165262
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 2 | On the mechanism, we demonstrated that DNAJB8 could interact with TP53 and inhibit the ubiquitination degradation of TP53, leading to MDR1 upregulation which promotes colon cancer L-OHP resistance. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 3 | On the mechanism, we demonstrated that DNAJB8 could interact with TP53 and inhibit the ubiquitination degradation of TP53, leading to MDR1 upregulation which promotes colon cancer L-OHP resistance. | Oxaliplatin | tumor protein p53 | Homo sapiens |