Pub. Date : 2022 Jan 28
PMID : 35163465
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TMZ is an alkylating agent whose cytotoxicity is modulated by O6-methylguanine-DNA methyltransferase (MGMT), whose expression is determined by MGMT gene promoter methylation status. | Temozolomide | O-6-methylguanine-DNA methyltransferase | Homo sapiens |
| 2 | TMZ is an alkylating agent whose cytotoxicity is modulated by O6-methylguanine-DNA methyltransferase (MGMT), whose expression is determined by MGMT gene promoter methylation status. | Temozolomide | O-6-methylguanine-DNA methyltransferase | Homo sapiens |
| 3 | TMZ is an alkylating agent whose cytotoxicity is modulated by O6-methylguanine-DNA methyltransferase (MGMT), whose expression is determined by MGMT gene promoter methylation status. | Temozolomide | O-6-methylguanine-DNA methyltransferase | Homo sapiens |
| 4 | Moreover, NS398+TMZ counteracted the resistance in T98G preventing the TMZ-induced COX-2, beta-catenin, MGMT, and SOX-2 up-regulation. | Temozolomide | O-6-methylguanine-DNA methyltransferase | Homo sapiens |
| 5 | Moreover, NS398+TMZ counteracted the resistance in T98G preventing the TMZ-induced COX-2, beta-catenin, MGMT, and SOX-2 up-regulation. | Temozolomide | O-6-methylguanine-DNA methyltransferase | Homo sapiens |