Title : Prevention of Lipotoxicity in Pancreatic Islets with Gammahydroxybutyrate.

Pub. Date : 2022 Feb 4

PMID : 35159354






1 Functional Relationships(s)
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1 We found that GHB prevented the generation of palmitate-induced reactive oxygen species and the associated lipotoxic inhibition of glucose-stimulated insulin secretion while increasing the NADPH/NADP+ ratio. Sodium Oxybate 2,4-dienoyl CoA reductase 1, mitochondrial Mus musculus