Title : Dissecting TET2 Regulatory Networks in Blood Differentiation and Cancer.

Pub. Date : 2022 Feb 6

PMID : 35159097






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 During active demethylation, transcription factors (TFs) recruit TET enzymes (TET1, 2, and 3) to specific gene regulatory regions to first catalyze the oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and subsequently to higher oxidized cytosine derivatives. 5-Methylcytidine 5'-monophosphate tet methylcytosine dioxygenase 1 Homo sapiens