Title : GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival.

Pub. Date : 2022 Feb 2

PMID : 35159039






1 Functional Relationships(s)
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1 Here we report a p53-independent mechanism responsible for Growth Factor Independence-1 (GFI1) support of MM cell survival by its modulation of sphingolipid metabolism to increase the sphingosine-1-phosphate (S1P) level regardless of the p53 status. Sphingolipids tumor protein p53 Homo sapiens