Title : Combretastatin A4-loaded poly(lactic-co-glycolic acid)/soybean lecithin nanoparticles with enhanced drug dissolution rate and antiproliferation activity.

Pub. Date : 2022 Feb 9

PMID : 35139789






1 Functional Relationships(s)
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1 Results:CA4 NPs prepared with a low organic/water phase ratio (1:20) and high drug/PLGA mass ratio (1:2.5) exhibited a uniform hydrodynamic particle size of 142 nm; zeta potential of -1.66 mV; and encapsulation efficacy and drug loading of 92.1% and 28.3%, respectively. Water carbonic anhydrase 4 Homo sapiens