Title : Preparation and Study of Folate Modified Albumin Targeting Microspheres.

Pub. Date : 2022

PMID : 35126516






5 Functional Relationships(s)
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1 Preparation and Study of Folate Modified Albumin Targeting Microspheres. Folic Acid albumin Homo sapiens
2 In this study, folate modified bovine serum albumin was successfully synthesized, while preparation of Nintedanib albumin microspheres (ND-FSA NPs) as a carrier was carried out via electrospinning technology. Folic Acid albumin Homo sapiens
3 Folate modified albumin was used to enhance the targeting potential of the prepared microspheres. Folic Acid albumin Homo sapiens
4 It is worth noting that incorporation of Nintedanib into folic acid modified albumin microspheres resulted in an enhanced uptake of the drug into MCF-7 breast cancer cells coupled with higher inhibition rate. Folic Acid albumin Homo sapiens
5 Altogether, incorporation of Nintedanib into folate modified albumin microspheres is a new approach to improve water solubility and targeting effect of the drug. Folic Acid albumin Homo sapiens