Title : Abnormal antithrombin III with defective serine protease binding (antithrombin III "Denver").

Pub. Date : 1986 Mar

PMID : 3512602






4 Functional Relationships(s)
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Protein Name
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1 When thrombin-antithrombin (TAT) complexes were formed by incubating with excess thrombin, SDS-polyacrylamide gel electrophoresis (PAGE) analysis revealed that half the patient AT-III formed TAT complexes while the remainder migrated as free AT-III. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens
2 The patient"s nonreacting AT-III (AT-III "Denver"), isolated by affinity chromatography, showed CIE and SDS-PAGE migration patterns characteristic of normal AT-III but failed to bind thrombin or Xa. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens
3 The patient"s nonreacting AT-III (AT-III "Denver"), isolated by affinity chromatography, showed CIE and SDS-PAGE migration patterns characteristic of normal AT-III but failed to bind thrombin or Xa. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens
4 The patient"s nonreacting AT-III (AT-III "Denver"), isolated by affinity chromatography, showed CIE and SDS-PAGE migration patterns characteristic of normal AT-III but failed to bind thrombin or Xa. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens