Title : The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione.

Pub. Date : 2022 Jan 29

PMID : 35123263






3 Functional Relationships(s)
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1 The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione. Cysteine surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 Taken together, these data indicate that Cys-488 in spike RBD is required for SARS-CoV-2 spike functions and infectivity, and could be a target of anti-SARS-CoV-2 therapeutics. Cysteine surface glycoprotein Severe acute respiratory syndrome coronavirus 2
3 Taken together, these data indicate that Cys-488 in spike RBD is required for SARS-CoV-2 spike functions and infectivity, and could be a target of anti-SARS-CoV-2 therapeutics. Cysteine surface glycoprotein Severe acute respiratory syndrome coronavirus 2