Title : Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis.

Pub. Date : 2022 Jan 15

PMID : 35114452






1 Functional Relationships(s)
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1 CONCLUSION: Atractylenolide-1 is a potential drug for the treatment of colitis by suppressing inflammation via the SPHK1/PI3K/AKT axis and by targeting SPHK1 and B4GAT2 to regulate fructose/galactose-related metabolism, thereby regulating the composition of the intestinal flora. atractylenolide- thymoma viral proto-oncogene 1 Mus musculus