Title : Hypoxanthine-guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP.

Pub. Date : 2022 Apr

PMID : 35114018






2 Functional Relationships(s)
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1 Hypoxanthine-guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP. Inosine Monophosphate hypoxanthine phosphoribosyltransferase 1 Homo sapiens
2 Here, the reverse reaction of HGPRT from the thermophilic bacterium Hungateiclostridium thermocellum was studied in the presence of IMP and pyrophosphate. Inosine Monophosphate hypoxanthine phosphoribosyltransferase 1 Homo sapiens