Title : Agrin Promotes Non-Small Cell Lung Cancer Progression and Stimulates Regulatory T Cells via Increasing IL-6 Secretion Through PI3K/AKT Pathway.

Pub. Date : 2021

PMID : 35111682






2 Functional Relationships(s)
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1 In the mouse model, Agrin downregulation alleviated NSCLC cell growth and Treg infiltration in vivo. treg agrin Mus musculus
2 Our results indicated that Agrin promotes tumor cell growth and Treg infiltration via increasing IL-6 expression and secretion through PI3K/AKT pathway in NSCLC. treg agrin Mus musculus