Pub. Date : 2022
PMID : 35111229
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, tangeretin increased the expression of both connexin26 (Cx26) and gap junction function, which may mediate the bystander effects of cisplatin or sorafenib. | Sorafenib | gap junction protein beta 2 | Homo sapiens |
| 2 | In addition, tangeretin increased the expression of both connexin26 (Cx26) and gap junction function, which may mediate the bystander effects of cisplatin or sorafenib. | Sorafenib | gap junction protein beta 2 | Homo sapiens |
| 3 | Taken together, the present study revealed a novel molecular mechanism by which tangeretin may inhibit the proliferation of CRPC cells, by affecting the Cx26/AKT/AR pathway, to synergistically increase the sensitivity of CRPC cells to sorafenib and cisplatin. | Sorafenib | gap junction protein beta 2 | Homo sapiens |